16.9.11

DOST explores GM mosquito applications against dengue

Part of its advocacy to find solutions against dengue, the Department of Science and Technology (DOST) explores the possibility of using genetically-modified mosquito (GMM) to curb the population of dengue-carrying Aedes aegypti mosquitoes.

In a conference organized by the DOST, experts from the University of California and the Oxitec Technologies of the United Kingdom (UK) presented the aspects of genetically-engineered male mosquitoes to the scientists and biotechnology experts of DOST and other concerned agencies at the Hyatt Hotel last 12 September 2011.

“Male mosquitoes were basically used because they don’t bite humans and they have significant role in the reproduction of mosquitoes,” said Dr. Anthony James, http://www.blogger.com/img/blank.gifProfessor at the Department of Microbiology and Molecular Genetics, University of California. Through the “Release of Insects carrying a Dominant Lethal” (RIDL) technology, male mosquitoes are engineered to contain a gene that can be passed on to female mosquito by mating. The mating results to unviable female mosquito offspring.

“The gene targets a certain muscle on a female mosquito that affects the development of wings – thus flightless female mosquitoes are produced.” The flightless female mosquito can’t seek host to take blood meal. Thus, it can’t spread the dengue virus,” said Dr. James. “This is also lethal for female mosquitoes because they are more likely to be eaten by predators. Continuous release of male mosquitoes in the wild will eventually cut-off the population of deadly mosquitoes,” added Dr. James. Read more

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